We were introduced to Metronome by Mattias Nygren, CEO of Tarsier, who described the game as a sound-driven adventure, at which point we weren't quite sure what to expect. The basis for the story of the game was dreamed up from children's books and Asian horror films. The concept of the game originated from Per Bergman and Bjorn Sunesson, two of the nine-person development team over at Team Tarsier. Sound-driven gameplay takes audio to previously unimaginable heights. The title is truly a genre-defying experience, combining platforming, adventure, and third-person shooter aspects with a myriad of other features that have never been seen before. 2015 46:3370–3374.Hidden in the back of Kentia Hall, the slums of E3, we found a real gem in The City of Metronome, which was unlike anything we have ever seen. Benefits of stroke treatment using a mobile stroke unit compared with standard management: the BEST‐MSU study run‐in phase. 2017 88:1305–1312.īowry R, Parker S, Rajan SS, Yamal JM, Wu TC, Richardson L, Noser E, Persse D, Jackson K, Grotta JC. Reduction in time to treatment in prehospital telemedicine evaluation and thrombolysis. Taqui A, Cerejo R, Itrat A, Briggs FB, Reimer AP, Winners S, Organek N, Buletko AB, Sheikhi L, Cho SM, Buttrick M, Donohue MM, Khawaja Z, Wisco D, Frontera JA, Russman AN, Hustey FM, Kralovic DM, Rasmussen P, Uchino K, Hussain MS. Telemedicine in prehospital stroke evaluation and thrombolysis: taking stroke treatment to the doorstep. Itrat A, Taqui A, Cerejo R, Briggs F, Cho SM, Organek N, Reimer AP, Winners S, Rasmussen P, Hussain MS, Uchino K Cleveland Pre‐Hospital Acute Stroke Treatment Group. Effect of the use of ambulance‐based thrombolysis on time to thrombolysis in acute ischemic stroke: a randomized clinical trial. 2012 11:397–404.Įbinger M, Winter B, Wendt M, Weber JE, Waldschmidt C, Rozanski M, Kunz A, Koch P, Kellner PA, Gierhake D, Villringer K, Fiebach JB, Grittner U, Hartmann A, Mackert BM, Endres M, Audebert HJ STEMO Consortium. Diagnosis and treatment of patients with stroke in a mobile stroke unit versus in hospital: a randomised controlled trial. Walter S, Kostopoulos P, Haass A, Keller I, Lesmeister M, Schlechtriemen T, Roth C, Papanagiotou P, Grunwald I, Schumacher H, Helwig S, Viera J, Körner H, Alexandrou M, Yilmaz U, Ziegler K, Schmidt K, Dabew R, Kubulus D, Liu Y, Volk T, Kronfeld K, Ruckes C, Bertsch T, Reith W, Fassbender K. Conclusions In a densely populated urban area with a high number of intermediary stroke centers, MSU care was associated with substantially quicker time to thrombolysis compared with conventional ambulance care.Īcute ischemic stroke geocoding mobile stroke unit prehospital stroke care tissue plasminogen activator. In multivariable analysis, MSU care was associated with a mean decrease in dispatch-to-thrombolysis time of 29.7 minutes (95% CI, 6.9-52.5) compared with conventional care. Compared with patients receiving conventional care, patients receiving MSU care were significantly more likely to be picked up closer to a higher mean number of designated stroke centers in a 2.0-mile radius (4.8 versus 2.7, P=0.002). Patients receiving MSU care had significantly shorter dispatch-to-thrombolysis time than patients receiving conventional care (mean: 61.2 versus 91.6 minutes P=0.001). We identified 66 patients treated or transported by MSU and 19 patients transported by conventional ambulance. We estimated mean differences in the primary outcome between both groups, adjusting for clinical, demographic, and geographic factors, including numbers of nearby designated stroke centers and population density. Our exposure was MSU care, and our primary outcome was dispatch-to-thrombolysis time. The comparison group included patients transported to our hospitals via conventional ambulance for acute ischemic stroke during the same hours of MSU operation (Monday to Friday, 9 am to 5 pm). Methods and Results We evaluated patients from the METRONOME (Metropolitan New York Mobile Stroke) registry with suspected acute ischemic stroke who were transported by a bi-institutional MSU operating in Manhattan, New York, from October 2016 to September 2017. Whether this advantage exists in densely populated urban areas with many proximate hospitals is unclear. Background Mobile stroke units (MSUs) reduce time to intravenous thrombolysis in acute ischemic stroke.
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